Hereditary vs. Familial vs. Sporadic Cancer

This lesson introduces the key differences between hereditary, familial, and sporadic cancers. It also describes how molecular pathology, and genetic testing can help doctors tell the difference between these three types of cancer. Each type of cancer is also described in greater detail along with their differences and similarities. We also provide some questions to ask your doctor about the testing and diagnostic process.  By understanding these differences, patients can make informed decisions about their health and cancer risk management.

By the end of this lesson, readers will be able to:

• Explain the difference between germline and somatic mutations
• Explain the difference between sporadic, hereditary and familial cancer
• Describe how family history and molecular biomarkers can be used to distinguish somatic, hereditary and familial cancer