Arun Seth

Dr. Arun Seth

Director and Professor, Sunnybrook Health Sciences Centre, University of Toronto, Toronto


Dr. Seth is a Molecular cancer researcher with broad based expertise in leading and directing research activities in oncogenesis and molecular diagnostics. Over three decades, led the creation, design, and initiation of independent research work, securing funding through government, charity, and industry sources. The founding Editor-in-Chief for the journal “Cancer Genomics and Proteomics” and an Associate Editor for “Cancer Research” he also serves as an editorial board member of five cancer related international journals.

Awarded tenure by the National Cancer Institute of the National Institutes of Health, the world’s premier center of cancer research, as an independent position at NCI-NIH Group Leader in Molecular Oncology studying the functional biology of oncogenes. Continuation of that work in Toronto led to the characterization of novel genes associated with breast tumors and angiogenesis.

After joining the University of Toronto Department of Laboratory Medicine he launched a second independent laboratory developing molecular diagnostic tests at Women’s College Hospital (WCH). After the merger of WCH and Sunnybrook Health Science Centre (SHSC), he moved the cancer research team to Sunnybrook Research Institute (SRI), and, as Director of Molecular Diagnostics Laboratory, expanded clinical molecular diagnostic services within SHSC. Since then he created and is director of the SRI Genomics Centre supporting research by clinical departments at Sunnybrook and other major hospitals as they embrace genomic approaches to cancer screening and diagnostics. He is now focused on studying breast and prostate cancer genome anatomy to characterize molecular targets that have diagnostic and therapeutic applications in cancer by rapidly screening samples for somatically acquired mutations with known biological functions.

Funded Projects

Assessment of Progestin Response Potential in Grade 2 Endometrial Endometrioid Adenocarcinoma and Interrogation of Biomarkers Associated with Progestin Resistance »

Discovery of markers predictive of progestin therapy response in endometrial atypical hyperplasia and low grade endometrioid adenocarcinoma »

Research Specialties

Research Interests

  • Breast
  • Gastrointestinal
  • Molecular Pathology
  • Urological

Contact for Collaboration

Sunnybrook Health Sciences Centre, University of Toronto
Pathologists and Researchers who are interested in being part of the OMPRN: